Check out the companies making headlines before the bell. Grail — Shares cratered 47% after the company said a trial of one of its drugs missed its primary endpoint and failed to show statistically significant Stage III-IV cancer reduction. Blue Owl Capital — Shares slid nearly 3%, a day after after the private market and alternative assets manager fell 5.9% following the sale of $1.4 billion in loans . Opendoor Technologies — The residential real estate sales platform saw shares rise 19%. Fourth-quarter revenue of $736 million beat the LSEG consensus estimate of $549 million. Opendoor sees its first-quarter adjusted EBITDA loss in the low to mid $30 million range, versus the FactSet consensus call for a loss of $32.2 million. Management said that the company is “driving to Adjusted Net Income positive by the end of 2026, measured on a 12-month go-forward basis.” Akamai Technologies — Shares of the cloud computing company dropped about 10% in the after-hours session after Akamai gave disappointing first-quarter guidance. Akamai said it sees first-quarter adjusted earnings ranging between $1.50 and $1.67 per share, compared to the $1.75 per share consensus estimate from analysts polled by LSEG.
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